Mark R. Spaller

Associate Professor, Medical Education
Adjunct Associate Professor, Biological Sciences
Adjunct Associate Professor, Chemistry

Biological Sciences
B.S. University of Texas at Austin
Ph.D. University of Texas at Austin

Related Links

Selected Publications

Knafo S, Sánchez-Puelles C, Palomer E, Delgado I, Draffin JE, Mingo J, Wahle T, Kaleka K, Mou L, Pereda-Perez I, Klosi E, Faber EB, Chapman HM, Lozano-Montes L, Ortega-Molina A, Ordóñez-Gutiérrez L, Wandosell F, Viña J, Dotti CG, Hall RA, Pulido R, Gerges NZ, Chan AM, Spaller MR, Serrano M, Venero C, Esteban JA. "PTEN recruitment controls synaptic and cognitive function in Alzheimer's models." Nat Neurosci. 2016, 19, 443-53

Marshall J, Wong KY, Rupasinghe CN, Tiwari R, Zhao X, Berberoglu ED, Sinkler C, Liu J, Lee I, Parang K, Spaller MR, Hüttemann M, Goebel DJ. "Inhibition of N-methyl-D-aspartate-induced retinal neuronal death by polyarginine peptides Is linked to the attenuation of stress-induced hyperpolarization of the inner mitochondrial membrane potential." Biol Chem. 2015, 290, 22030-48

Pal K, Pletnev AA, Dutta SK, Wang E, Zhao R, Baral A, Yadav VK, Aggarwal S, Krishnaswamy S, Alkharfy KM, Chowdhury S, Spaller MR, Mukhopadhyay D. "Inhibition of endoglin-GIPC interaction inhibits pancreatic cancer cell growth." Mol Cancer Ther. 2014, 13, 2264-75

Amacher JF, Zhao R, Spaller MR, Madden DR. "Chemically modified peptide scaffolds target the CFTR-associated ligand PDZ domain." PLoS One 2014, 19;9(8):e103650

LeBlanc BW, Iwata M, Mallon AP, Rupasinghe CN, Goebel DJ, Marshall J, Spaller MR, Saab CY. "A cyclic peptide targeted against PSD-95 blocks central sensitization and attenuates thermal hyperalgesia." Neuroscience. 2010, 167, 490-500

Sharma SC, Memic A, Rupasinghe CN, Duc AC, Spaller MR. "T7 phage display as a method of peptide ligand discovery for PDZ domain proteins." Biopolymers. 2009, 92, 183-93