Mingqin Chang

Post-doctoral Scholar

Vesicles that form on the endoplasmic reticulum (ER) and are bound for the Golgi apparatus are coated in a complex of proteins known as Coat Protein Complex II (COPII). COPII proteins are highly conserved throughout eukaryotes. Metazoans have few genes encoding each COPII component. By contrast, plants have expanded these gene families. Evidence has suggested that these gene expansions underly increased functional diversification required to pattern and build plant cells. It is interesting to discover what detailed functions Plant COPII genes have acquired during these gene expansions.


Class of 1978 Life Sciences Center, 304
HB 6044


  • Bachelor's: Tianjin Medical University, China
  • MSc: Beijing Normal University, China
  • PhD: University of Massachusetts Amherst, USA

Selected Publications

  • *Ma, Q., *Chang, M., Drakakaki, G., & Russinova, E. (2022). (*Co-first author) Selective chemical probes can untangle the complexity of the plant cell endomembrane system. Current Opinion in Plant Biology, 68, 102223. https://doi.org/10.1016/j.pbi.2022.102223

    Chang, M., Wu, S.-Z., Ryken, S. E., O'Sullivan, J. E., & Bezanilla, M. (2022). COPII Sec23 proteins form isoform-specific endoplasmic reticulum exit sites with differential effects on polarized growth. The Plant Cell, koab229. https://doi.org/10.1093/plcell/koab229

    Shao, Y., Cheng, Y., Pang, H., Chang, M., He, F., Wang, M., Davis, D. J., Zhang, S., Betz, O., Fleck, C., Dai, T., Madahhosseini, S., Wilkop, T., Jernstedt, J., & Drakakaki, G. (2021). Investigation of Salt Tolerance Mechanisms Across a Root Developmental Gradient in Almond Rootstocks. Frontiers in Plant Science, 11. https://doi.org/10.3389/fpls.2020.595055

    *Mallett, D. R., *Chang, M., Cheng, X., & Bezanilla, M. (2019). (*Co-first author) Efficient and modular CRISPR‐Cas9 vector system for Physcomitrella patens. Plant Direct, 3(9).

    van Gisbergen, P.A.C., Wu, S.-Z., Chang, M., Pattavina, K.A., Bartlett, M.E., and Bezanilla, M. (2018). An ancient Sec10–formin fusion provides insights into actin-mediated regulation of exocytosis. The Journal of Cell Biology 217, 945–957.

    Liu, P., Qi, M., Wang, Y., Chang, M., Liu, C., Sun, M., Yang, W., and Ren, H. (2014). Arabidopsis RAN1 Mediates Seed Development through Its Parental Ratio by Affecting the Onset of Endosperm Cellularization. Molecular Plant 7, 1316–1328.