Mary Lou Guerinot

Professor of Biological Sciences
Ronald and Deborah Harris Professorship in the Sciences
Professor in the Molecular and Cellular Biology Graduate Program

I study the molecular mechanisms of metal ion uptake and its regulation in prokaryotic and eukaryotic cells using a combined genetic, molecular, and biochemical approach. My goal is to understand the functional connections between genes, proteins, metabolites, and mineral ions. I’m also looking at the reduction of iron by a family of membrane-bound Fe(III) reductases and metal metabolism in the symbiosis between Bradyrhizobium japonicum and soybeans.

Curriculum Vitae
HB 6044
Biological Sciences
B.S. Cornell University
Ph.D. Dalhousie University

Selected Publications

Hong, S., S.A. Kim, M.L. Guerinot and C.R. McClung.  2013.  Reciprocal interaction of the circadian clock with the Fe homeostasis network in Arabidopsis thaliana.  Plant Physiol. 163: 893-903. PMCID: PMC3561027

Schroeder, J.I., E. Delhaize, W.B. Frommer, M.L. Guerinot, M.J. Harrison, L. Herrera-Estrella, T. Horie, L.V. Kochian, R. Munns, N.K. Nishizawa, Y.-F. Tsay and D. Sanders.  2013.  Using membrane transporters to improve crops for sustainable food production.  Nature 497: 60-66.

Hosmani, P.S., T. Kamiya, J. Danku S. Naseer, N. Geldner, M.L. Guerinot and D.E. Salt.  2013.   A dirigent-domain containing protein is part of the machinery required for formation of the lignin-based Casparian strip in the root.  Proc. Natl. Acad. Sci. U.S.A.  110:14498-503

Zhang, M, S.R.M. Pinson, L. Tarpley, X. Huang, B. Lahner, E. Yakubova, M.L. Guerinot, and D.E. Salt.  2013.  Mapping and validation of quantitative trait loci associated with concentrations of 16 elements in unmilled rice grain.  Theor. Appl. Genet.  10.1007/s00122-013-2207-5

Palmer, C., M.N. Hindt, H. Schmidt, S. Clemens and M.L. Guerinot.  2013.  MYB10 and MYB72 Are required for growth under iron-limiting conditions.  PLoS Genet.  9(11):e1003953

Norton, G.J.,  A. Douglas, B. Lahner, E. Yakubova, M.L. Guerinot, S.R.M. Pinson, L. Tarpley, G.C. Eizenga, S.P. McGrath, F-J. Zhao, M.R. Islam, S. Islam, G. Duan, Y. Zhu, D.E. Salt, A.A. Meharg and A.H. Price.  2014.  Genome wide association mapping of grain arsenic, copper, molybdenum and zinc in rice (Oryza sativa L.) grown at four international field sites.  PLoS One 9(2):e89685.

Socha, A. and M.L. Guerinot.  2014.  Mn-euvering manganese: the role of transporter gene family members in manganese uptake and mobilization in plants.  Front. Plant Sci. 5:106. doi: 10.3389/fpls.2014.00106