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My research investigates the impacts of both non-essential and essential metals on maternal and child health. I primarily study metal impacts on birth outcomes, early life growth, and cardiometabolic health with a focus on epigenetic mediators of toxicant exposures and metals toxicity in the context of nutritional status and complex environmental mixtures.
Epidemiology
A complete list of my published work can be found at:
https://www.ncbi.nlm.nih.gov/myncbi/caitlin.howe.1/bibliography/public/
Yim G, McGee G, Gallagher L, Baker E, Jackson BP, Calafat AM, Cook Botelho J, Gilbert-Diamond D, Karagas MR, Romano ME, Howe CG. Metals and per- and polyfluoroalkyl substances mixtures and birth outcomes in the New Hampshire Birth Cohort Study: Beyond single-class mixture approaches. Chemosphere. 2023;329:138644.
Howe CG, Foley HB, Farzan SF, Chavez TA, Johnson M, Meeker JD, Bastain TM, Marsit CJ, Breton CV. Urinary metals and maternal circulating extracellular vesicle microRNA in the MADRES pregnancy cohort. Epigenetics. 2022;17(10):1128-1142.
Howe CG, Foley HB, Kennedy EM, Eckel SP, Chavez TA, Faham D, Grubbs BH, Al-Marayati L, Lerner D, Suglia S, Bastain TM, Marsit CJ, Breton CV. Extracellular vesicle microRNA in early versus late pregnancy with birth outcomes in the MADRES study. Epigenetics. 2022;17(3):269-285.
Howe CG, Margetaki K, Vafeiadi M, Roumeliotaki T, Karachalious M, Kogevinas M, McConnell R, Eckel SP, Conti DV, Kippler M, Farzan SF, Chatzi L. Prenatal metal mixtures and child blood pressure in the Rhea mother-child cohort in Greece. Environmental Health. 2021;20(1):1-16.
Howe CG, Claus Henn B, Eckel SP, Farzan SF, Grubbs BH, Chavez TA, Hodes TL, Faham D, Al-Marayati L, Lerner D, Quimby A, Twogood S, Richards MJ, Meeker D, Bastain TM, Breton CV. Prenatal metal mixtures and birth weight for gestational age in a predominately lower-income Hispanic pregnancy cohort in Los Angeles. Environmental Health Perspectives. 2020;128(11):117001.
Howe CG, Cox B, Fore R, Jungius J, Kvist T, Lent S, Miles HE, Salas LA, Rifas-Shiman S, Starling AP, Yousefi P, Ladd-Acosta C, Baccarelli A, et al. Maternal gestational diabetes mellitus and newborn DNA methylation: findings from the pregnancy and childhood epigenetics consortium. Diabetes Care. 2020;43(1):98-105.