Thomas P. Jack
Professor
Appointments
Professor of Biological Sciences
Professor in the Molecular and Cellular Biology Graduate Program
Leadership Fellow, Partnership for Undergraduate Life Sciences Education (PULSE) Vision and Change
Area of Expertise
Plant molecular biology,
Genetics
Biography
I'm interested in the molecular basis for how cells become different from one another during development. This is a very general question that is faced by all multicellular organisms. I have chosen to address this question in plants, specifically in flowers, which consist of an array of cell, tissue, and organ types.
Education
B.S., Haverford College
Ph.D., Yale University
Publications
Xu, Y., Prunet, N., Gan, E.-S., Wang, Y., Stewart, D., Wellmer, F., Huang, J., Yamaguchi, N., Tatsumi, Y., Kojima, M., Kiba, T., Sakakibara, H., Jack, T. P., Meyerowitz, E. M., Ito, T. (2018). SUPERMAN regulates floral whorl boundaries through control of auxin biosynthesis. EMBO J. 37: e97499. doi: 10.15252/embj.201797499.
Prunet, N., Yang, W., Das, P., Meyerowit, E.M., Jack, T.P. (2017) SUPERMAN prevents class B gene expression and promotes stem cell termination in the fourth whorl of Arabidopsis thaliana flowers. Proc Natl Acad Sci U S A. 2017 Jul 3;114(27):7166-7171. doi: 10.1073/pnas.1705977114. Epub 2017 Jun 20.
Brancaccio-Taras, L., Pape-Lindstrom, P. A., Peteroy-Kelly, M., Aguirre, K. M., Awong-Taylor, J., Balser, T. C., Cahill, M., Frey, G., Jack, T., Kelrick, M., Marley, K. E., Miller, K. G., Osgood, M. P., Romano, S. L. Uzman, J. A., Zhao. J. (2016). The PULSE Vision & Change Rubrics: A valid and equitable tool to measure life sciences department transformation at all institution types. CBE Life Sci Educ. 2016 Winter; 15(4): ar60. doi: 10.1187/cbe.15-12-0260 PMCID: PMC5132357 PMID: 27856548.
Prunet, N., Jack, T. P., and Meyerowitz, E. M. (2016) Live confocal imaging of Arabidopsis flower buds. Dev Biol. 2016 Mar 15. pii: S0012-1606(16)30066-5. doi: 10.1016/j.ydbio.2016.03.018. [Epub ahead of print]
Prunet, N., Morel, P., Champelovier, P., Thierry, A.-M., Negrutiu, I., Jack, T., and Trehin, C. (2015). SQUINT promotes stem cell homeostasis and floral meristem termination in Arabidopsis through APETALA2 and CLAVATA signaling. J. Ex. Bot. 66, 6905-6916.
Pape-Lindstrom, P. A., Jack, T., Miller, K. G., Aguirre, K. M., Awong-Taylor, J., Balser, T. C., Awong-Taylor, J., Brancaccio-Taras, L., Marley, K. E., Osgood, M. P., Peteroy-Kelly, M., Romano, S. L. (2015). PULSE pilot certification results. J. Microbiol. Ed. 16, 127-129.
Wellmer, F., Bowman, J. L., Davies, B., Ferrandiz, C., Fletcher J. C., Franks, R. G., Graciet, E., Gregis, V., Ito, T., Jack, T. P., Jiao, Y., Kater, M. M., Ma, H., Meyerowitz, E. M., Prunet, N., and Riechmann, J. L. (2014). Flower Development: Open Questions and Future Directions. In Methods in Molecular Biology - Flower Development: Methods and Protocols (F. Wellmer and J.-L. Riechmann editors), 103-124.
Prunet, N. and Jack, T. (2014). Flower development in Arabidopsis – there's more to it than learning your ABCs. In Methods in Molecular Biology - Flower Development: Methods and Protocols (F. Wellmer and J.-L. Riechmann editors), 3-33.
Gauthier, A., and Jack, T. (2014). The Professor and the instructional designer: a course design journey. Transformations: Liberal Arts in the Digital Age.
Aguirre, K. M., Balser, T. C., Jack, T., Marley, K. E., Miller, K. G., Osgood, M. P., Pape-Lindstrom, P. A., and Romano, S. L. (2013). PULSE Vision & Change Rubrics. CBE-Life Sciences Education 12, 579-581. (corresponding author).
Jacob, N., Lee-Brown, M., Allen, T., Gusky, S., and Jack, T. (2013). Catalysing educational transformation: The PULSE Project. GARNish Newsletter 20, 18-21.
Nag, A., and Jack, T. (2010). Sculpting the flower: the role of miRNAs in flower development. Current Topics Dev. Biol. 91, 349-378.
Nag, A., King. S., and Jack, T. (2009). miR319a targeting of TCP4 is critical for petal growth and development in Arabidopsis. Proc. Natl. Acad. Sci. USA 106, 22534-22539.
Swaminathan, K., Peterson, K., and Jack, T. (2008). The plant B3 superfamily. Trends in Plant Science 13, 647-655.
Piwarzyk, E., Yang, Y., and Jack, T. (2007). The conserved C-terminal motifs of the Arabidopsis proteins AP3 and PI are dispensable for function. Plant Phys. 145, 1495-1505. (This work received a Faculty of 1000 citation)
Nag, A., Yang, Y., and Jack, T. (2007). DORNRÖSCHEN-LIKE, an AP2 gene, is necessary for stamen emergence in Arabidopsis. Plant Mol. Biol. 65, 219-232. (Work featured in cover photograph.)
Yang, Y and T Jack, Defining Subdomains of the K Domain Important for Protein-Protein Interactions of Plant MADS Proteins, Plant Molecular Biology , 55:1 (2004) 45-59.
Jack, T (2004) Molecular and Genetic Mechanisms of Floral Control, The Plant Cell , 16 S1-S17.
Yang, Y, H Xiang, and T Jack, pistillata-5 , an Arabidopsis B class mutant with strong defects in petal but not in stamen development, Plant Journal , (2003) 33 177-188.
Yang, Y, L Fanning, and T Jack, The K domain mediates heterodimerization of the Arabidopsis floral organ identity proteins, APETALA3 and PISTILLATA, Plant Journal , 33 (2003) 47-60.
Jack, T, Flower Development," Encyclopedia of Plant and Crop Science , R Goodman (ed.) (2003) 464-467.
Prunet, N., Yang, W., Das, P., Meyerowitz, E.M., and T.P. Jack. (2017) SUPERMAN prevents class b gene expression and promotes stem cell termination in the fourth whorl of Arabidopsis thaliana flowers. Proc. Natl. Acad. Sci. USA doi: 10.1073/pnas.1705977114 (http://www.pnas.org/content/early/2017/06/19/1705977114)
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