Menu
- Undergraduate
- Graduate
- Research
- Foreign Study Program
- Seminars, News & Events
- People
- SEPA
Back to Top Nav
Back to Top Nav
Back to Top Nav
My research interests are to understand how microbes change over time. Recent advances in DNA sequencing technologies brought us an avalanche of data: thousands of genomes and terabases of environmental DNA (metagenomes). I mine these data sets to assess the impact of horizontal gene transfer on microbial populations, find new ways to characterize microbial communities, and track down genomic signatures of microbial adaptations.
Roman Kogay, Yuri I Wolf, Eugene V Koonin, and Olga Zhaxybayeva (2020): "Selection for Reducing Energy Cost of Protein Production Drives the GC Content and Amino Acid Composition Bias in Gene Transfer Agents", mBio, 11:e01206-20.
Chase WR, Zhaxybayeva O, Rocha J, Cosgrove DJ, Shapiro LR. (2020) "Global cellulose biomass, horizontal gene transfers and domain fusions drive microbial expansin evolution." New Phytol., 226:921-938.
Kogay R, Neely TB, Birnbaum DP, Hankel CR, Shakya M, Zhaxybayeva O. (2019): "Machine-learning classification suggests that many alphaproteobacterial prophages may instead be gene transfer agents", Genome Biol Evol., evz206.
Bauer KM, Dicovitsky R, Pellegrini M, Zhaxybayeva O, Ragusa MJ. (2019): "The structure of a highly-conserved picocyanobacterial protein reveals a Tudor domain with an RNA-binding function", J Biol Chem., 294:14333-14344.