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Cilia and flagella, which project from the cell surface of many different cell types, are involved in cell motility. They also act like antenna and sense environmental conditions. They are taken apart at each cell division and reassembled by the two, newly formed daughter cells. Our lab is studying the steps required for the disassembly of cilia and flagella to occur prior to the start of cell division.
Bloodgood, Robert A., Joseph Tetreault, and Roger D Sloboda. (2019). The Chlamydomonas flagellar membrane glycoprotein FMG-1B is necessary for expression of force at the flagellar surface. Journal of Cell Science, 132, jcs233429. doi:10.1242/jcs.233429
First Person – Robert Bloodgood and Roger Sloboda. (2019). Journal of Cell Science 132, jcs237461. doi:10.1242/jcs.23746
Mizuno, Katsutoshi and Sloboda, Roger D. (2017). Protein arginine methyltransferases interact with intraflagellar transport particles and change location during flagellar growth and resorption. Molecular Biology of the Cell, 28(9):1208-1222. doi: 10.1091/mbc.E16-11-0774. PMID: 28298486
Sloboda, Roger D. (2016). Purification and Localization of Intraflagellar Transport Particles and Polypeptides, in: Cytoskeleton; Methods and Protocols, 3rd ed., pp. 119-137. doi 10.1007/978-1-4939-3124-8_6