Imaging Facility Publications 2015 - present


Frequency of spontaneous neurotransmission at individual boutons corresponds to the size of the readily releasable pool of vesicles.  Ralowicz AJ, Hokeness S, Hoppa MB. J Neurosci. 2024 Feb 21:e1253232024. doi: 10.1523/JNEUROSCI.1253-23.2024. Online ahead of print. PMID: 38383495

Determinants of cytoplasmic microtubule depolymerization during ciliogenesis in Chlamydomonas.  Dougherty LL, Avasthi P. Life Sci Alliance. 2023 Oct 9;7(1):e202302287. doi: 10.26508/lsa.202302287. Print 2024 Jan. PMID: 37813489

Cyclin A/Cdk1 promotes chromosome alignment and timely mitotic progression. Valles SY, Godek KM, Compton DA. bioRxiv [Preprint]. 2023 Dec 21:2023.12.21.572788. doi: 10.1101/2023.12.21.572788. PMID: 38187612

A new GUV-based assay to reconstitute membrane tethering in vitro demonstrates the vesicle tethering ability of the selective autophagy scaffold Atg11. Andhare D, Ragusa MJ. bioRxiv [Preprint]. 2023 Dec 19:2023.12.19.572332. doi: 10.1101/2023.12.19.572332. PMID: 38187578

The ER membrane protein complex restricts mitophagy by controlling BNIP3 turnover. Delgado JM, Shepard LW, Lamson SW, Liu SL, Shoemaker CJ. EMBO J. 2024 Jan;43(1):32-60. doi: 10.1038/s44318-023-00006-z. Epub 2023 Dec 15. PMID: 38177312

The cystic fibrosis treatment Trikafta affects the growth, viability, and cell wall of Aspergillus fumigatus biofilms. Jones JT, Morelli KA, Vesely EM, Puerner CTS, Pavuluri CK, Ross BS, van Rhijn N, Bromley MJ, Cramer RA. mBio. 2023 Oct 31;14(5):e0151623. doi: 10.1128/mbio.01516-23. Epub 2023 Oct 13. PMID: 37830825

The USP46 deubiquitylase complex increases Wingless/Wnt signaling strength by stabilizing Arrow/LRP6.  Spencer ZT, Ng VH, Benchabane H, Siddiqui GS, Duwadi D, Maines B, Bryant JM, Schwarzkopf A, Yuan K, Kassel SN, Mishra A, Pimentel A, Lebensohn AM, Rohatgi R, Gerber SA, Robbins DJ, Lee E, Ahmed Y. Nat Commun. 2023 Oct 5;14(1):6174. doi: 10.1038/s41467-023-41843-0. PMID: 37798281

Early zygotic gene product Dunk interacts with anillin to regulate Myosin II during Drosophila cleavage.  Chen J, Verissimo AF, Kull AR, He B. Mol Biol Cell. 2023 Sep 1;34(10):ar102. doi: 10.1091/mbc.E22-02-0046. Epub 2023 Jul 26. PMID: 37494082

Cellulose synthase-like D movement in the plasma membrane requires enzymatic activity. Wu SZ, Chaves AM, Li R, Roberts AW, Bezanilla M. J Cell Biol. 2023 Jun 5;222(6):e202212117. doi: 10.1083/jcb.202212117. Epub 2023 Apr 18. PMID: 37071416

Optogenetic Inhibition of Rho1-Mediated Actomyosin Contractility Coupled with Measurement of Epithelial Tension in Drosophila Embryos. Guo H, Swan M, He B. J Vis Exp. 2023 Apr 14;(194). doi: 10.3791/65314. PMID: 37125810

ACAT1/SOAT1 Blockade Suppresses LPS-Mediated Neuroinflammation by Modulating the Fate of Toll-like Receptor 4 in Microglia.  Li H, Huynh TN, Duong MT, Gow JG, Chang CCY, Chang TY. Int J Mol Sci. 2023 Mar 15;24(6):5616. doi: 10.3390/ijms24065616. PMID: 36982689

Acute ACAT1/SOAT1 Blockade Increases MAM Cholesterol and Strengthens ER-Mitochondria Connectivity. Harned TC, Stan RV, Cao Z, Chakrabarti R, Higgs HN, Chang CCY, Chang TY. Int J Mol Sci. 2023 Mar 14;24(6):5525. doi: 10.3390/ijms24065525. PMID: 36982602

Lithium-induced ciliary lengthening sparks Arp2/3 complex-dependent endocytosis. Bigge BM, Dougherty LL, Avasthi P. Mol Biol Cell. 2023 Apr 1;34(4):ar26. doi: 10.1091/mbc.E22-06-0219. Epub 2023 Feb 8. PMID: 36753380
Initial ciliary assembly in Chlamydomonas requires Arp2/3 complex-dependent endocytosis. Bigge BM, Rosenthal NE, Avasthi P. Mol Biol Cell. 2023 Apr 1;34(4):ar24. doi: 10.1091/mbc.E22-09-0443. Epub 2023 Feb 8. PMID: 36753382

USP47 deubiquitylates Groucho/TLE to promote Wnt-β-catenin signaling. Kassel S, Hanson AJ, Benchabane H, Saito-Diaz K, Cabel CR, Goldsmith L, Taha M, Kanuganti A, Ng VH, Xu G, Ye F, Picker J, Port F, Boutros M, Weiss VL, Robbins DJ, Thorne CA, Ahmed Y, Lee E. Sci Signal. 2023 Feb 7;16(771):eabn8372. doi: 10.1126/scisignal.abn8372. Epub 2023 Feb 7. PMID: 36749823 

The ERK activator, BCI, inhibits ciliogenesis and causes defects in motor behavior, ciliary gating, and cytoskeletal rearrangement. Dougherty LL, Dutta S, Avasthi P. Life Sci Alliance. 2023 Mar 13;6(6):e202301899. doi: 10.26508/lsa.202301899. Print 2023 Jun. PMID: 36914265

A pluripotent developmental state confers a low fidelity of chromosome segregation. Deng C, Ya A, Compton DA, Godek KM. Stem Cell Reports. 2023 Feb 14;18(2):475-488. doi: 10.1016/j.stemcr.2022.12.008. Epub 2023 Jan 12. PMID: 36638786

An optogenetic tool to inhibit RhoA in Drosophila embryos. Guo H, Swan M, He B. STAR Protoc. 2023 Jan 3;4(1):101972. doi: 10.1016/j.xpro.2022.101972.

Optimized fluorescent proteins for 4-color and photoconvertible live-cell imaging in Neurospora crassa. Wang Z, Bartholomai BM, Loros JJ, Dunlap JC. Fungal Genet Biol. 2023 Jan;164:103763. doi: 10.1016/j.fgb.2022.103763. Epub 2022 Dec 5. PMID: 36481248

Postinfluenza Environment Reduces Aspergillus fumigatus Conidium Clearance and Facilitates Invasive Aspergillosis In Vivo. Liu KW, Grau MS, Jones JT, Wang X, Vesely EM, James MR, Gutierrez-Perez C, Cramer RA, Obar JJ. mBio. 2022 Dec 20;13(6):e0285422. doi: 10.1128/mbio.02854-22. Epub 2022 Nov 15. PMID: 36377895

PRD-2 mediates clock-regulated perinuclear localization of clock gene RNAs within the circadian cycle of Neurospora. Bartholomai BM, Gladfelter AS, Loros JJ, Dunlap JC. Proc Natl Acad Sci U S A. 2022 Aug 2;119(31):e2203078119. doi: 10.1073/pnas.2203078119. PMID: 35881801

Actomyosin activity-dependent apical targeting of Rab11 vesicles reinforces apical constriction. Chen W, He B. J Cell Biol. 2022 Jun 6;221(6):e202103069. doi: 10.1083/jcb.202103069. PMID: 35404399

Acat1/Soat1 knockout extends the mutant Npc1 mouse lifespan and ameliorates functional deficiencies in multiple organelles of mutant cells. Rogers MA, Chang CCY, Maue RA, Melton EM, Peden AA, Garver WS, Lee J, Schroen P, Huang M, Chang TY. Proc Natl Acad Sci U S A. 2022 May 3;119(18):e2201646119. doi: 10.1073/pnas.2201646119. PMID: 35507892

An Alanine Aminotransferase Is Required for Biofilm-Specific Resistance of Aspergillus fumigatus to Echinocandin Treatment. Kerkaert JD, Le Mauff F, Wucher BR, Beattie SR, Vesely EM, Sheppard DC, Nadell CD, Cramer RA. mBio. 2022 Apr 26;13(2):e0293321. doi: 10.1128/mbio.02933-21. PMID: 35254131

Evidence for a Role of the Lateral Ectoderm in Drosophila Mesoderm Invagination. Guo H, Huang S, He B. Front Cell Dev Biol. 2022 Apr 25;10:867438. doi: 10.3389/fcell.2022.867438. eCollection 2022. PMID: 35547820

Dimerization-dependent membrane tethering by Atg23 is essential for yeast autophagy.  Hawkins WD, Leary KA, Andhare D, Popelka H, Klionsky DJ, Ragusa MJ. Cell Rep. 2022 Apr 19;39(3):110702. doi: 10.1016/j.celrep.2022.110702. PMID: 35443167

A Comparative Analysis of the Membrane Binding and Remodeling Properties of Two Related Sorting Nexin Complexes Involved in Autophagy. Reinhart EF, Katzenell S, Andhare D, Bauer KM, Ragusa MJ. Biochemistry. 2022 Apr 14. doi: 10.1021/acs.biochem.2c00007

The cell polarity determinant Dlg1 facilitates epithelial invagination by promoting tissue-scale mechanical coordination. Fuentes MA, He B. Development. 2022 Mar 15;149(6):dev200468. doi: 10.1242/dev.200468. Epub 2022 Mar 18. PMID: 35302584

PTEN Regulates Dendritic Arborization by Decreasing Microtubule Polymerization Rate. Getz SA, Tariq K, Marchand DH, Dickson CR, Howe Vi JR, Skelton PD, Wang W, Li M, Barry JM, Hong J, Luikart BW. J Neurosci. 2022 Mar 9;42(10):1945-1957. doi: 10.1523/JNEUROSCI.1835-21.2022. Epub 2022 Jan 31. PMID: 35101965

Arf6 anchors Cdr2 nodes at the cell cortex to control cell size at division.  Opalko HE, Miller KE, Kim HS, Vargas-Garcia CA, Singh A, Keogh MC, Moseley JB. J Cell Biol. 2022 Feb 7;221(2):e202109152. doi: 10.1083/jcb.202109152. Epub 2021 Dec 27. PMID: 34958661

Toll-Dorsal signaling regulates the spatiotemporal dynamics of yolk granule tubulation during Drosophila cleavage. Reed S, Chen W, Bergstein V, He B. Dev Biol. 2022 Jan;481:64-74. doi: 10.1016/j.ydbio.2021.09.009. Epub 2021 Oct 7. PMID: 34627795

Facile method to incorporate high-affinity ACAT/SOAT1 inhibitor F12511 into stealth liposome-based nanoparticle and demonstration of its efficacy in blocking cholesteryl ester biosynthesis without overt toxicity in neuronal cell culture. De La Torre AL, Smith C, Granger J, Anderson FL, Harned TC, Havrda MC, Chang CCY, Chang TY. J Neurosci Methods. 2021 Dec 7;367:109437. doi: 10.1016/j.jneumeth.2021.109437. Online ahead of print. PMID: 34890698

Quantitative single molecule RNA-FISH and RNase-free cell wall digestion in Neurospora crassa. Bartholomai BM, Gladfelter AS, Loros JJ, Dunlap JC. Fungal Genet Biol. 2021 Nov;156:103615. doi: 10.1016/j.fgb.2021.103615. Epub 2021 Aug 20. PMID: 34425213

The Burkholderia cenocepacia Type VI Secretion System Effector TecA Is a Virulence Factor in Mouse Models of Lung Infection. Loeven NA, Perault AI, Cotter PA, Hodges CA, Schwartzman JD, Hampton TH, Bliska JB. mBio. 2021 Oct 26;12(5):e0209821. doi: 10.1128/mBio.02098-21. Epub 2021 Sep 28. PMID: 34579569

Toll-Dorsal signaling regulates the spatiotemporal dynamics of yolk granule tubulation during Drosophila cleavage. Reed S, Chen W, Bergstein V, He B. Dev Biol. 2021 Oct 7;481:64-74. doi: 10.1016/j.ydbio.2021.09.009. Online ahead of print. PMID: 34627795

Photoprotection during iron deficiency is mediated by the bHLH transcription factors PYE and ILR3.  Akmakjian GZ, Riaz N, Guerinot ML. Proc Natl Acad Sci U S A. 2021 Oct 5;118(40):e2024918118. doi: 10.1073/pnas.2024918118. PMID: 34580211

Sequestration of the exocytic SNARE Psy1 into multiprotein nodes reinforces polarized morphogenesis in fission yeast.  Miller KE, Magliozzi JO, Picard NA, Moseley JB. Mol Biol Cell. 2021 Oct 1;32(20):ar7. doi: 10.1091/mbc.E20-05-0277. PMID: 34347508

Mff oligomerization is required for Drp1 activation and synergy with actin filaments during mitochondrial division. Liu A, Kage F, Higgs HN. Mol Biol Cell. 2021 Oct 1;32(20):ar5. doi: 10.1091/mbc.E21-04-0224. Epub 2021 Aug 4. PMID: 34347505

SABRE populates ER domains essential for cell plate maturation and cell expansion influencing cell and tissue patterning. Cheng X, Bezanilla M. Elife. 2021 Mar 9;10:e65166. doi: 10.7554/eLife.65166. PMID: 33687329

A Heterogeneously Expressed Gene Family Modulates the Biofilm Architecture and Hypoxic Growth of Aspergillus fumigatus. Kowalski CH, Morelli KA, Stajich JE, Nadell CD, Cramer RA. mBio. 2021 Feb 16;12(1):e03579-20. doi: 10.1128/mBio.03579-20. PMID: 33593969

A highly conserved glutamic acid in ALFY inhibits membrane binding to aid in aggregate clearance. Reinhart EF, Litt NA, Katzenell S, Pellegrini M, Yamamoto A, Ragusa MJ. Traffic. 2021 Jan;22(1-2):23-37. doi: 10.1111/tra.12771. Epub 2020 Dec 1. PMID: 33225481

The phosphatase inhibitor Sds23 promotes symmetric spindle positioning in fission yeast.  Schutt KL, Moseley JB.
Cytoskeleton (Hoboken). 2020 Dec 6; doi: 10.1002/cm.21648. Epub 2020 Dec 6. PMID: 33280247

Separable roles for RanGTP in nuclear and ciliary trafficking of a kinesin-2 subunit.  Huang S, Dougherty LL, Avasthi P.  J Biol Chem. 2020 Nov 24:jbc.RA119.010936. doi: 10.1074/jbc.RA119.010936. Online ahead of print. PMID: 33234597

Receptor-mediated clustering of FIP200 bypasses the role of LC3 lipidation in autophagy.  Ohnstad AE, Delgado JM, North BJ, Nasa I, Kettenbach AN, Schultz SW, Shoemaker CJ. EMBO J. 2020 Nov 23;39(24):e104948. doi: 10.15252/embj.2020104948. Online ahead of print. PMID: 33226137

A highly conserved glutamic acid in ALFY inhibits membrane binding to aid in aggregate clearance.  Reinhart EF, Litt NA, Katzenell S, Pellegrini M, Yamamoto A, Ragusa MJ. Traffic. 2020 Nov 22. doi: 10.1111/tra.12771. Online ahead of print. PMID: 33225481

Functional Analysis of the Rice Type-B Response Regulator RR22. Yamburenko MV, Worthen JM, Zeenat A, Azhar BJ, Swain S, Couitt AR, Shakeel SN, Kieber JJ, Schaller GE. Front Plant Sci. 2020 Nov 10;11:577676. doi: 10.3389/fpls.2020.577676. eCollection 2020. PMID: 33240296

Cancer-associated mutations in the condensin II subunit CAPH2 cause genomic instability through telomere dysfunction and anaphase chromosome bridges. Weyburne E, Bosco G.  J Cell Physiol. 2020 Oct 20. doi: 10.1002/jcp.30113. Online ahead of print. PMID: 33078399

Overexpression of Mdm36 reveals Num1 foci that mediate dynein-dependent microtubule sliding in budding yeast.  Omer S, Brock K, Beckford J, Lee WL. J Cell Sci. 2020 Oct 15;133(20):jcs246363. doi: 10.1242/jcs.246363. PMID: 32938686

The Third Coiled Coil Domain of Atg11 Is Required for Shaping Mitophagy Initiation Sites.  Margolis HK, Katzenell S, Leary KA, Ragusa MJ. J Mol Biol. 2020 Oct 2;432(21):5752-5764. doi: 10.1016/j.jmb.2020.08.025. Epub 2020 Sep 5. PMID: 32896530

Fungal biofilm architecture produces hypoxic microenvironments that drive antifungal resistance.  Kowalski CH, Morelli KA, Schultz D, Nadell CD, Cramer RA. PNAS September 8, 2020 117 (36) 22473-22483; first published August 26, 2020

Fission yeast Pak1 phosphorylates anillin-like Mid1 for spatial control of cytokinesis. Magliozzi JO, Sears J, Cressey L, Brady M, Opalko HE, Kettenbach AN, Moseley JB J Cell Biol. 2020 Aug 3;219(8) pii: e201908017. doi: 10.1083/jcb.201908017. PMID: 32421151

Tumor microtubes connect pancreatic cancer cells in an Arp2/3 complex-dependent manner. Latario CJ, Schoenfeld LW, Howarth CL, Pickrell LE, Begum F, Fischer DA, Grbovic-Huezo O, Leach SD, Sanchez Y, Smith KD, Higgs HN.

Freeze-frame imaging of synaptic activity using SynTagMA. Perez-Alvarez A, Fearey BC, O'Toole RJ, Yang W, Arganda-Carreras I, Lamothe-Molina PJ, Moeyaert B, Mohr MA, Panzera LC, Schulze C, Schreiter ER, Wiegert JS, Gee CE, Hoppa MB, Oertner TG. Nat Commun. 2020 May 18;11(1):2464. doi: 10.1038/s41467-020-16315-4. PMID: 32424147

The Photoconvertible Fluorescent Probe, CaMPARI, Labels Active Neurons in Freely-Moving Intact Adult Fruit Flies. Edwards KA, Hoppa MB, Bosco G. Front Neural Circuits. 2020 May 8;14:22. doi: 10.3389/fncir.2020.00022. eCollection 2020. PMID: 32457580

In vivo analysis of formin dynamics in the moss P. patens reveals functional class diversification. van Gisbergen P, Wu SZ, Cheng X, Pattavina KA, Bezanilla M. J Cell Sci. 2020 Feb 12;133(3). pii: jcs233791. doi: 10.1242/jcs.233791. PMID: 31969472

SapTrap Assembly of Caenorhabditis elegans MosSCI Transgene Vectors. Fan X, De Henau S, Feinstein J, Miller SI, Han B, Frøkjær-Jensen C, Griffin EE. G3 (Bethesda). 2020 Feb 6;10(2):635-644. doi: 10.1534/g3.119.400822. PMID: 31848219

Toxoplasma gondii Parasitophorous Vacuole Membrane-Associated Dense Granule Proteins Regulate Maturation of the Cyst Wall. Guevara RB, Fox BA, Bzik DJ. mSphere. 2020 Jan 15;5(1). pii: e00851-19. doi: 10.1128/mSphere.00851-19. PMID: 31941814

Fungal biofilm morphology impacts hypoxia fitness and disease progression. Kowalski CH, Kerkaert JD, Liu KW, Bond MC, Hartmann R, Nadell CD, Stajich JE, Cramer RA. Nat Microbiol. 2019 Dec;4(12):2430-2441. doi: 10.1038/s41564-019-0558-7. Epub 2019 Sep 23. PMID: 31548684

Pten loss results in inappropriate excitatory connectivity. Skelton PD, Frazel PW, Lee D, Suh H, Luikart BW. Mol Psychiatry. 2019 Nov;24(11):1627-1640. doi: 10.1038/s41380-019-0412-6. Epub 2019 Apr 9. PMID: 30967683

Condensin II subunit NCAPH2 associates with shelterin protein TRF1 and is required for telomere stability. Wallace HA, Rana V, Nguyen HQ, Bosco G. J Cell Physiol. 2019 Nov;234(11):20755-20768. doi: 10.1002/jcp.28681. Epub 2019 Apr 26. PMID: 31026066

The phosphatase inhibitor Sds23 regulates cell division symmetry in fission yeast. Schutt KL, Moseley JB. Mol Biol Cell. 2019 Nov 1;30(23):2880-2889. doi: 10.1091/mbc.E19-05-0254. Epub 2019 Sep 25. PMID: 31553675

Myeloid Acat1/Soat1 KO attenuates pro-inflammatory responses in macrophages and protects against atherosclerosis in a model of advanced lesions. Melton EM, Li H, Benson J, Sohn P, Huang LH, Song BL, Li BL, Chang CCY, Chang TY. J Biol Chem. 2019 Oct 25;294(43):15836-15849. doi: 10.1074/jbc.RA119.010564. Epub 2019 Sep 8. PMID: 31495784

Toxoplasma gondii Intravacuolar-Network-Associated Dense Granule Proteins Regulate Maturation of the Cyst Matrix and Cyst Wall. Guevara RB, Fox BA, Falla A, Bzik DJ. mSphere. 2019 Oct 16;4(5). pii: e00487-19. doi: 10.1128/mSphere.00487-19. PMID: 31619500

Two distinct actin filament populations have effects on mitochondria, with differences in stimuli and assembly factors. Fung TS, Ji WK, Higgs HN, Chakrabarti R. J Cell Sci. 2019 Sep 23;132(18). pii: jcs234435. doi: 10.1242/jcs.234435. PMID: 31413070

Increased levels of superoxide dismutase suppress meiotic segregation errors in aging oocytes. Perkins AT, Greig MM, Sontakke AA, Peloquin AS, McPeek MA, Bickel SE. Chromosoma. 2019 Sep;128(3):215-222. doi: 10.1007/s00412-019-00702-y. Epub 2019 Apr 29. PMID: 31037468

Subcellular control of membrane excitability in the axon. Alpizar SA, Cho IH, Hoppa MB. Curr Opin Neurobiol. 2019 Aug;57:117-125. doi: 10.1016/j.conb.2019.01.020. Epub 2019 Feb 20. Review. PMID: 30784979

Neural circuitry of social learning in Drosophila requires multiple inputs to facilitate inter-species communication. Kacsoh BZ, Bozler J, Hodge S, Bosco G. Commun Biol. 2019 Aug 13;2:309. doi: 10.1038/s42003-019-0557-5. eCollection 2019. PMID: 31428697

Type-B response regulators of rice play key roles in growth, development and cytokinin signaling. Worthen JM, Yamburenko MV, Lim J, Nimchuk ZL, Kieber JJ, Schaller GE. Development. 2019 Jul 10;146(13). pii: dev174870. doi: 10.1242/dev.174870. PMID: 31160418

Single-Cell Analyses Confirm the Critical Role of LRP6 for Wnt Signaling in APC-Deficient Cells. Cabel CR, Alizadeh E, Robbins DJ, Ahmed Y, Lee E, Thorne CA. Dev Cell. 2019 Jun 17;49(6):827-828. doi: 10.1016/j.devcel.2019.05.039. No abstract available.  PMID: 31211991

Essential long-range action of Wingless/Wnt in adult intestinal compartmentalization. Tian A, Duwadi D, Benchabane H, Ahmed Y. PLoS Genet. 2019 Jun 13;15(6):e1008111. doi: 10.1371/journal.pgen.1008111. eCollection 2019 Jun. PMID: 31194729

Stable Pom1 clusters form a glucose-modulated concentration gradient that regulates mitotic entry. Allard CAH, Opalko HE, Moseley JB. Elife. 2019 May 3;8. pii: e46003. doi: 10.7554/eLife.46003. PMID: 31050341

An Ssd1 Homolog Impacts Trehalose and Chitin Biosynthesis and Contributes to Virulence in Aspergillus fumigatus. Thammahong A, Dhingra S, Bultman KM, Kerkaert JD, Cramer RA. mSphere. 2019 May 8;4(3). pii: e00244-19. doi: 10.1128/mSphere.00244-19. PMID: 31068436

A complex containing lysine-acetylated actin inhibits the formin INF2. A M, Fung TS, Kettenbach AN, Chakrabarti R, Higgs HN. Nat Cell Biol. 2019 May;21(5):592-602. doi: 10.1038/s41556-019-0307-4. Epub 2019 Apr 8. PMID: 30962575

Developmental regulation of Wnt signaling by Nagk and the UDP-GlcNAc salvage pathway. Neitzel LR, Spencer ZT, Nayak A, Cselenyi CS, Benchabane H, Youngblood CQ, Zouaoui A, Ng V, Stephens L, Hann T, Patton JG, Robbins D, Ahmed Y, Lee E. Mech Dev. 2019 Apr;156:20-31. doi: 10.1016/j.mod.2019.03.002. Epub 2019 Mar 20. PMID:3090459

The ESCRT-Related ATPase Vps4 Is Modulated by Interferon during Herpes Simplex Virus 1 Infection. Cabrera JR, Manivanh R, North BJ, Leib DA. MBio. 2019 Mar 5;10(2). pii: e02567-18. doi: 10.1128/mBio.02567-18. PMID:30837340

A Context-Dependent Role for the RNF146 Ubiquitin Ligase in Wingless/Wnt Signaling in Drosophila. Wang Z, Tacchelly-Benites O, Noble GP, Johnson MK, Gagné JP, Poirier GG, Ahmed Y. Genetics. 2019 Mar;211(3):913-923. doi: 10.1534/genetics.118.301393. Epub 2018 Dec 28. MID: 30593492

Single-molecule dynamics of the P granule scaffold MEG-3 in the Caenorhabditis elegans zygote. Wu Y, Han , Gauvin TJ, Smith J, Singh A, Griffin EE.Mol Biol Cell. 2019 Feb 1;30(3):333-345. doi: 10.1091/mbc.E18-06-0402. Epub 2018 Dec 12.PMID:30540524

Loss of Neurofascin-186 Disrupts Alignment of AnkyrinG Relative to Its Binding Partners in the Axon Initial Segment. Alpizar SA, Baker AL, Gulledge AT, Hoppa MB. Front Cell Neurosci. 2019 Jan 22;13:1. doi: 10.3389/fncel.2019.00001. eCollection 2019. PMID: 30723396

New Drosophila Long-Term Memory Genes Revealed by Assessing Computational Function Prediction Methods. Kacsoh BZ, Barton S, Jiang Y, Zhou N, Mooney SD, Friedberg I, Radivojac P, Greene CS, Bosco G.G3 (Bethesda). 2019 Jan 9;9(1):251-267. doi: 10.1534/g3.118.200867. PMID: 30463884

Roles for Ena/VASP proteins in FMNL3-mediated filopodial assembly. Young LE, Latario CJ, Higgs HN. J Cell Sci. 2018 Oct 29;131(21). pii: jcs220814. doi: 10.1242/jcs.220814. PMID: 30373894

Coordination of Chloroplast Development through the Action of the GNC and GLK Transcription Factor Families. Zubo YO, Blakley IC, Franco-Zorrilla JM, Yamburenko MV, Solano R, Kieber JJ, Loraine AE, Schaller GE. Plant Physiol. 2018 Sep;178(1):130-147. doi: 10.1104/pp.18.00414. Epub 2018 Jul 12. PMID: 30002259

Rapid diffusion-state switching underlies stable cytoplasmic gradients in the Caenorhabditis elegans zygote. Wu Y, Han B, Li Y, Munro E, Odde DJ, Griffin EE. Proc Natl Acad Sci U S A. 2018 Sep 4;115(36):E8440-E8449. doi: 10.1073/pnas.1722162115. Epub 2018 Jul 24. PMID: 30042214

A pseudo-receiver domain in Atg32 is required for mitophagy.  Xia X, Katzenell S, Reinhart EF, Bauer KM, Pellegrini M, Ragusa MJ. Autophagy. 2018;14(9):1620-1628. doi: 10.1080/15548627.2018.1472838. Epub 2018 Aug 1. PMID: 29909755

Drosophila species learn dialects through communal living. Kacsoh BZ, Bozler J, Bosco G. PLoS Genet. 2018 Jul 19;14(7):e1007430. doi: 10.1371/journal.pgen.1007430. eCollection 2018 Jul. Erratum in: PLoS Genet. 2018 Nov 27;14(11):e1007825.  PMID: 30024883

Focal Adhesions Undergo Longitudinal Splitting into Fixed-Width Units. Young LE, Higgs HN. Curr Biol. 2018 Jul 9;28(13):2033-2045.e5. doi: 10.1016/j.cub.2018.04.073. Epub 2018 Jun 14. PMID: 9910076

Exploiting mitochondrial and metabolic homeostasis as a vulnerability in NF1 deficient cells.  Allaway RJ, Wood MD, Downey SL, Bouley SJ, Traphagen NA, Wells JD, Batra J, Melancon SN, Ringelberg C, Seibel W, Ratner N, Sanchez Y. Oncotarget. 2017 Jul 18;9(22):15860-15875. doi: 10.18632/oncotarget.19335. eCollection 2018 Mar 23. PMID: 29662612

Cell size-dependent regulation of Wee1 localization by Cdr2 cortical nodes. Allard CAH, Opalko HE, Liu KW, Medoh U, Moseley JB. J Cell Biol. 2018 May 7;217(5):1589-1599. doi: 10.1083/jcb.201709171. Epub 2018 Mar 7. PMID: 29514920

Axin phosphorylation in both Wnt-off and Wnt-on states requires the tumor suppressor APC. Tacchelly-Benites O, Wang Z, Yang E, Benchabane H, Tian A, Randall MP, Ahmed Y. PLoS Genet. 2018 Feb 6;14(2):e1007178. doi: 10.1371/journal.pgen.1007178. eCollection 2018 Feb. PMID: 29408853

INF2-mediated actin polymerization at the ER stimulates mitochondrial calcium uptake, inner membrane constriction, and division. Chakrabarti R, Ji WK, Stan RV, de Juan Sanz J, Ryan TA, Higgs HN. J Cell Biol. 2018 Jan 2;217(1):251-268. doi: 10.1083/jcb.201709111. Epub 2017 Nov 15. PMID: 29142021

Using Fluorescence In Situ Hybridization (FISH) to Monitor the State of Arm Cohesion in Prometaphase and Metaphase I Drosophila Oocytes. Perkins AT, Bickel SE. J Vis Exp. 2017 Dec 6;(130). doi: 10.3791/56802. PMID: 29286418

Receptor-mediated Drp1 oligomerization on endoplasmic reticulum. Ji WK, Chakrabarti R, Fan X, Schoenfeld L, Strack S, Higgs HN. J Cell Biol. 2017 Dec 4;216(12):4123-4139. doi: 10.1083/jcb.201610057. Epub 2017 Nov 20. PMID: 29158231

Cyclin A/Cdk1 modulates Plk1 activity in prometaphase to regulate kinetochore-microtubule attachment stability. Dumitru AMG, Rusin SF, Clark AEM, Kettenbach AN, Compton DA. Elife. 2017 Nov 20;6. pii: e29303. doi: 10.7554/eLife.29303. PMID:29154753

Nematocytes: Discovery and characterization of a novel anculeate hemocyte in Drosophila falleni and Drosophila phalerata. Bozler J, Kacsoh BZ, Bosco G. PLoS One. 2017 Nov 15;12(11):e0188133. doi: 10.1371/journal.pone.0188133. eCollection 2017. PMID: 29141015

Sodium Channel β2 Subunits Prevent Action Potential Propagation Failures at Axonal Branch Points. Cho IH, Panzera LC, Chin M, Hoppa MB. J Neurosci. 2017 Sep 27;37(39):9519-9533. doi: 10.1523/JNEUROSCI.0891-17.2017. Epub 2017 Sep 4. PMID: 28871036

Intestinal stem cell overproliferation resulting from inactivation of the APC tumor suppressor requires the transcription cofactors Earthbound and Erect wing. Tian A, Benchabane H, Wang Z, Zimmerman C, Xin N, Perochon J, Kalna G, Sansom OJ, Cheng C, Cordero JB, Ahmed Y. PLoS Genet. 2017 Jul 14;13(7):e1006870. doi: 10.1371/journal.pgen.1006870. eCollection 2017 Jul. PMID: 28708826

Dual Roles for Membrane Association of Drosophila Axin in Wnt Signaling. Wang Z, Tacchelly-Benites O, Yang E, Ahmed Y. PLoS Genet. 2016 Dec 13;12(12):e1006494. doi: 10.1371/journal.pgen.1006494. eCollection 2016 Dec. PMID: 27959917PLoS Genet. 2017 Jul 14;13(7):e1006870. doi: 10.1371/journal.pgen.1006870. eCollection 2017 Jul. PMID: 28708826

Intestinal stem cell overproliferation resulting from inactivation of the APC tumor suppressor requires the transcription cofactors Earthbound and Erect wing. Tian A, Benchabane H, Wang Z, Zimmerman C, Xin N, Perochon J, Kalna G, Sansom OJ, Cheng C, Cordero JB, Ahmed Y. PLoS Genet. 2017 Jul 14;13(7):e1006870. doi: 10.1371/journal.pgen.1006870. eCollection 2017 Jul. PMID: 28708826

Cytokinin induces genome-wide binding of the type-B response regulator ARR10 to regulate growth and development in Arabidopsis. Zubo YO, Blakley IC, Yamburenko MV, Worthen JM, Street IH, Franco-Zorrilla JM, Zhang W, Hill K, Raines T, Solano R, Kieber JJ, Loraine AE, Schaller GE. Proc Natl Acad Sci U S A. 2017 Jul 18;114(29):E5995-E6004. doi: 10.1073/pnas.1620749114. Epub 2017 Jul 3. PMID: 28673986

SUPERMAN prevents class B gene expression and promotes stem cell termination in the fourth whorl of Arabidopsis thaliana flowers. Prunet N, Yang W, Das P, Meyerowitz EM, Jack TP. Proc Natl Acad Sci U S A. 2017 Jul 3;114(27):7166-7171. doi: 10.1073/pnas.1705977114. Epub 2017 Jun 20. PMID:28634297

Cytokinin acts through the auxin influx carrier AUX1 to regulate cell elongation in the root. Street IH, Mathews DE, Yamburkenko MV, Sorooshzadeh A, John RT, Swarup R, Bennett MJ, Kieber JJ, Schaller GE. Development. 2016 Nov 1;143(21):3982-3993. Epub 2016 Oct 3. PMID: 27697901

Live confocal imaging of Arabidopsis flower buds. Prunet N, Jack TP, Meyerowitz EM. Dev Biol. 2016 Nov 1;419(1):114-120. doi: 10.1016/j.ydbio.2016.03.018. Epub 2016 Mar 15. PMID:6992363

Oxidative stress in oocytes during midprophase induces premature loss of cohesion and chromosome segregation errors. Perkins AT, Das TM, Panzera LC, Bickel SE. Proc Natl Acad Sci U S A. 2016 Nov 1;113(44):E6823-E6830. Epub 2016 Oct 17. PMID: 27791141

Actin filaments as dynamic reservoirs for Drp1 recruitment. Hatch AL, Ji WK, Merrill RA, Strack S, Higgs HN. Mol Biol Cell. 2016 Oct 15;27(20):3109-3121. Epub 2016 Aug 24. PMID: 27559132

The ADP-ribose polymerase Tankyrase regulates adult intestinal stem cell proliferation during homeostasis in Drosophila. Wang Z, Tian A, Benchabane H, Tacchelly-Benites O, Yang E, Nojima H, Ahmed Y. Development. 2016 May 15;143(10):1710-20. doi: 10.1242/dev.127647. PMID: 27190037

Wnt pathway activation by ADP-ribosylation. Yang E, Tacchelly-Benites O, Wang Z, Randall MP, Tian A, Benchabane H, Freemantle S, Pikielny C, Tolwinski NS, Lee E, Ahmed Y. Nat Commun. 2016 May 3;7:11430. doi: 10.1038/ncomms11430. PMID: 27138857

Heterochromatin-Associated Proteins HP1a and Piwi Collaborate to Maintain the Association of Achiasmate Homologs in Drosophila Oocytes. Giauque CC, Bickel SE. Genetics. 2016 May;203(1):173-89. doi: 10.1534/genetics.115.186460. Epub 2016 Mar 16. PMID: 26984058

Wnt/Wingless Pathway Activation Is Promoted by a Critical Threshold of Axin Maintained by the Tumor Suppressor APC and the ADP-Ribose Polymerase Tankyrase. Wang Z, Tacchelly-Benites O, Yang E, Thorne CA, Nojima H, Lee E, Ahmed Y. Genetics. 2016 May;203(1):269-81. doi: 10.1534/genetics.115.183244. Epub 2016 Mar 14. PMID: 26975665

Micron-scale plasma membrane curvature is recognized by the septin cytoskeleton. Bridges AA, Jentzsch MS, Oakes PW, Occhipinti P, Gladfelter AS. J Cell Biol. 2016 Apr 11;213(1):23-32. doi: 10.1083/jcb.201512029. Epub 2016 Apr 4. PMID:27044896

Regulation of Stem Cell Proliferation and Cell Fate Specification by Wingless/Wnt Signaling Gradients Enriched at Adult Intestinal Compartment Boundaries. Tian A, Benchabane H, Wang Z, Ahmed Y. PLoS Genet. 2016 Feb 4;12(2):e1005822. doi: 10.1371/journal.pgen.1005822. eCollection 2016 Feb. PMID:26845150

The cytokinin response factors modulate root and shoot growth and promote leaf senescence in Arabidopsis. Raines T, Shanks C, Cheng CY, McPherson D, Argueso CT, Kim HJ, Franco-Zorrilla JM, López-Vidriero I, Solano R, Vaňková R, Schaller GE, Kieber JJ. Plant J. 2016 Jan;85(1):134-47. doi: 10.1111/tpj.13097. PMID: 26662515

Cell type-dependent mechanisms for formin-mediated assembly of filopodia. Young LE, Heimsath EG, Higgs HN. Mol Biol Cell. 2015 Dec 15;26(25):4646-59. doi: 10.1091/mbc.E15-09-0626. Epub 2015 Oct 7. PMID: 26446836

SQUINT promotes stem cell homeostasis and floral meristem termination in Arabidopsis through APETALA2 and CLAVATA signalling. Prunet N, Morel P, Champelovier P, Thierry AM, Negrutiu I, Jack T, Trehin C. J Exp Bot. 2015 Nov;66(21):6905-16. doi: 10.1093/jxb/erv394. Epub 2015 Aug 12. PMID: 26269626

RNA Controls PolyQ Protein Phase Transitions. Zhang H, Elbaum-Garfinkle S, Langdon EM, Taylor N, Occhipinti P, Bridges AA, Brangwynne CP, Gladfelter AS. Mol Cell. 2015 Oct 15;60(2):220-30. doi: 10.1016/j.molcel.2015.09.017. PMID: 26474065

Assembly and turnover of short actin filaments by the formin INF2 and profilin. Gurel PS, A M, Guo B, Shu R, Mierke DF, Higgs HN. J Biol Chem. 2015 Sep 11;290(37):22494-506. doi: 10.1074/jbc.M115.670166. Epub 2015 Jun 29. PMID: 26124273

Coupling between cytoplasmic concentration gradients through local control of protein mobility in the Caenorhabditis elegans zygote. Wu Y, Zhang H, Griffin EE. Mol Biol Cell. 2015 Sep 1;26(17):2963-70. doi: 10.1091/mbc.E15-05-0302. Epub 2015 Jul 8. PMID: 26157168

The ARGOS gene family functions in a negative feedback loop to desensitize plants to ethylene. Rai MI, Wang X, Thibault DM, Kim HJ, Bombyk MM, Binder BM, Shakeel SN, Schaller GE. BMC Plant Biol. 2015 Jun 24;15:157. doi: 10.1186/s12870-015-0554-x. PMID: 26105742

Social communication of predator-induced changes in Drosophila behavior and germ line physiology. Kacsoh BZ, Bozler J, Ramaswami M, Bosco G. Elife. 2015 May 13;4. doi: 10.7554/eLife.07423. PMID: 25970035

Condensin II Regulates Interphase Chromatin Organization Through the Mrg-Binding Motif of Cap-H2. Wallace HA, Klebba JE, Kusch T, Rogers GC, Bosco G. G3 (Bethesda). 2015 Mar 9;5(5):803-17. doi: 10.1534/g3.115.016634. PMID: 25758823

Drosophila casein kinase I alpha regulates homolog pairing and genome organization by modulating condensin II subunit Cap-H2 levels. Nguyen HQ, Nye J, Buster DW, Klebba JE, Rogers GC, Bosco G. PLoS Genet. 2015 Feb 27;11(2):e1005014. doi: 10.1371/journal.pgen.1005014. eCollection 2015. PMID: 25723539

The formin FMNL3 assembles plasma membrane protrusions that participate in cell-cell adhesion. Gauvin TJ, Young LE, Higgs HN. Mol Biol Cell. 2015 Feb 1;26(3):467-77. doi: 10.1091/mbc.E14-07-1247. Epub 2014 Nov 26. PMID: 25428984

Shugoshin-1 balances Aurora B kinase activity via PP2A to promote chromosome bi-orientation. Meppelink A, Kabeche L, Vromans MJ, Compton DA, Lens SM. Cell Rep. 2015 Apr 28;11(4):508-15. doi: 10.1016/j.celrep.2015.03.052. Epub 2015 Apr 16. PMID: 25892238

A novel paradigm for nonassociative long-term memory in Drosophila: predator-induced changes in oviposition behavior. Kacsoh BZ, Bozler J, Hodge S, Ramaswami M, Bosco G. Genetics. 2015 Apr;199(4):1143-57. doi: 10.1534/genetics.114.172221. Epub 2015 Jan 29. PMID: 25633088

Numerical chromosomal instability mediates susceptibility to radiation treatment. Bakhoum SF, Kabeche L, Wood MD, Laucius CD, Qu D, Laughney AM, Reynolds GE, Louie RJ, Phillips J, Chan DA, Zaki BI, Murnane JP, Petritsch C, Compton DA. Nat Commun. 2015 Jan 21;6:5990. doi: 10.1038/ncomms6990. PMID: 25606712